Grignard reaction is classical synthesis method of alkylation's processes. We routinely prepare and makes use of Grignard reagents for the manufacture of intermediates and active ingredients for the markets of Pharmaceuticals and chemicals. Syntheses are performed at scales between some tens of kg and more than 500kg per batch because of local dry air condition.
Organic compounds in molecules into nitro (-O2) reaction. Aromatics of nitration is the preparation of aromatic nitro-compound the most important methods. Nitration reagent have nitric acid and denitration acyl bittern (NOX), four fluorine boric acid nitro cation, etc, and most important, the most commonly used is the mixture of sulfuric acid and nitric acid.
